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Melanotan II (MT2) is a synthetic analogue of alpha-melanocyte-stimulating hormone (alpha-MSH), a signal involved in skin pigmentation. It activates melanocortin receptors and is studied for its ability to stimulate melanin, the pigment responsible for skin colour and tanning. A small early human study observed increased pigmentation, but this does not establish long-term safety or validate this pen formulation. Reported effects include nausea, flushing and changes in moles or freckles. This entry identifies the labelled 10 mg pen format. For research purposes only; not an approved tanning treatment or a substitute for sun protection.